Prothena Corporation plc
1559053 - 9999999997-12-15485
Please note that this filing was generated from a paper submission to the
Securities and Exchange Commission and was not filed electronically.

<SUBMISSION>
<PAPER>
<ACCESSION-NUMBER>9999999997-12-015485
<TYPE>CERTNAS
<PUBLIC-DOCUMENT-COUNT>1
<FILING-DATE>20121217
<DATE-OF-FILING-DATE-CHANGE>20121217
<EFFECTIVENESS-DATE>20121217
<FILER>
<COMPANY-DATA>
<CONFORMED-NAME>Prothena Corp plc
<CIK>0001559053
<ASSIGNED-SIC>2834
<IRS-NUMBER>000000000
<STATE-OF-INCORPORATION>L2
<FISCAL-YEAR-END>1231
</COMPANY-DATA>
<FILING-VALUES>
<FORM-TYPE>CERTNAS
<ACT>34
<FILE-NUMBER>001-35676
<FILM-NUMBER>12028490
</FILING-VALUES>
<BUSINESS-ADDRESS>
<STREET1>25-28 NORTH WALL QUAY
<CITY>DUBLIN
<STATE>L2
<ZIP>DUBLIN 1
<PHONE>353 1 709 4700
</BUSINESS-ADDRESS>
<MAIL-ADDRESS>
<STREET1>25-28 NORTH WALL QUAY
<CITY>DUBLIN
<STATE>L2
<ZIP>DUBLIN 1
</MAIL-ADDRESS>
<FORMER-COMPANY>
<FORMER-CONFORMED-NAME>Neotope Corp Ltd
<DATE-CHANGED>20120926
</FORMER-COMPANY>
</FILER>
<DOCUMENT>
<TYPE>CERTNAS
<SEQUENCE>1
<FILENAME>9999999997-12-015485.paper
<DESCRIPTION>AUTO-GENERATED PAPER DOCUMENT
<TEXT>
This document was generated as part of a paper submission.
Please reference the Document Control Number 12028490 for access to the original document.
</TEXT>
</DOCUMENT>
</SUBMISSION>